Vitamin B6 (Activated) P5P50

Pyridoxal-5-phosphate (P5P) is the active metabolite of pyridoxine and is the predominant form of plasma B6.

P5P is required for proper absorption of B12 and magnesium, and for the production of gastric HCl. It is an important coenzyme in the metabolism of carbohydrates, fats, and proteins, and the elongation of essential fatty acids.

It is required for the production of antibodies and red blood cells. P5P facilitates the release of glycogen (used in energy production) from the liver and muscles. In addition, P5P helps maintain the balance of sodium and potassium, which regulates body fluids and promotes the healthy functioning of the nervous and musculoskeletal systems.

Vitamin B6, as pyridoxal-5-phosphate, has a well established role in the provision of glucose, thus contributing to the healthy maintenance of ongoing energy levels.

Vitamin B6 is a key cofactor in the breakdown of homocysteine. A deficiency of vitamin B6 may therefore lead to mpaired breakdown of homocysteine which, in turn, causes elevated levels of plasma homocysteine.

P5P is a crucial cofactor in the production and metabolism of brain neurotransmitters, thereby contributing to normal psychological function.

Vitamin B6 deficiency can cause a microcytic anaemia in which the concentration of erythrocytes is reduced, which may lead to symptoms of weakness, tiredness or fatigue.

Vitamin B6 also contributes to the regulation of hormonal activity and the normal function of the immune system.